Biofluid Profiling

Overview

A biological fluid can be excreted (such as sweat or urine), secreted (such as bile or milk), obtained with a needle (such as blood or cerebrospinal fluid), or develop as a pathological result (such as blister or cyst fluid). With advantages of safety, cost-efficiency and non-invasion, biofluids show high potential for monitoring health and disease, with great translational values, and unparalleled opportunities for clinical practice. Biofluids are an ideal source of material for the development of predictive or prognostic biomarkers or companion diagnostics using next-generation sequencing (NGS)-based assays. Biofluid profiling using RNA-seq can analyze and quantify RNA molecules in biofluid samples and enable biomarker discovery and development.

We provide a full range of biofluid profiling services to investigate the levels of RNA molecules in biofluid samples (such as whole blood, serum, plasma, lymph or cerebrospinal fluids, saliva, and sweat ) using high-throughput sequencing technologies for medical research. Our service is only for research use only, not for diagnostic procedures.

Features

• Detect novel transcripts, SNPs, InDels, or other variations
• Examine the sequences and quantity of RNAs
• Superior data quality: ≥80% bases with ≥Q30, >90% on average
• Rigorous quality control and fast turn-around times
• Professional bioinformatics analysis in an efficient and customizable way

References:

1. Lee Y H, Wong D T. Saliva: an emerging biofluid for early detection of diseases. American journal of dentistry, 2009, 22(4): 241.
2. Zhao W, Liu Y, Zhang C, et al. Multiple Roles of Exosomal Long Noncoding RNAs in Cancers. BioMed research international, 2019, 2019.