A biological fluid can be excreted (such as sweat or urine), secreted (such as bile or milk), obtained with a needle (such as blood or cerebrospinal fluid), or develop as a pathological result (such as blister or cyst fluid). With advantages of safety, cost-efficiency and non-invasion, biofluids show high potential for monitoring health and disease, with great translational values, and unparalleled opportunities for clinical practice. Biofluids are an ideal source of material for the development of predictive or prognostic biomarkers or companion diagnostics using next-generation sequencing (NGS)-based assays. Biofluid profiling using RNA-seq can analyze and quantify RNA molecules in biofluid samples and enable biomarker discovery and development.
We provide a full range of biofluid profiling services to investigate the levels of RNA molecules in biofluid samples (such as whole blood, serum, plasma, lymph or cerebrospinal fluids, saliva, and sweat ) using high-throughput sequencing technologies for medical research. Our service is only for research use only, not for diagnostic procedures.
Detect novel transcripts, SNPs, InDels, or other variations
Examine the sequences and quantity of RNAs
Superior data quality: ≥80% bases with ≥Q30, >90% on average
Rigorous quality control and fast turn-around times
Professional bioinformatics analysis in an efficient and customizable way
Explore how biofluid profiling using NGS helps researchers understand RNA dynamics and interactions in biofluids.
Biofluid microRNA sequencing comprehensively analyzes all microRNAs in the biofluid sample using a library size selection (15 - 30 nt) approach. Our service supports the development of non-invasive biomarkers.
Exosomal lncRNA sequencing examines global lncRNAs in exosomes. As exosomal lncRNAs are involved with tumorigenesis, tumor angiogenesis, and chemoresistance, this service can detect promising biomarkers for cancer.
Exosomal cicrRNA-Seq can quickly and efficiently obtain global information on exosomal circRNAs. Our single-base resolution technology allows the detection of circRNAs from very small amounts of cellular material.
Exosomal mRNA sequencing service can not only help you to profile exosomal mRNA with regard to the expression levels and dynamics but also understand the physiological roles, with or without knowledge of priori sequences.
By combining high-quality miRNA extraction, comprehensive expression analysis, disease biomarker correlation, and UMIs, our Circulating miRNAs Sequencing service ensures reliable and accurate profiling of cell-free miRNAs.