RNA is the other major nucleic acid besides DNA. RNA is unique in being able to store and transmit the information as well as process that information. Classically RNAs can be classified into messenger RNAs (mRNAs) and non-coding RNAs (ncRNAs). RNA biomarkers allow for a very early analysis of the appearance or evolution of diseases, a differential analysis of gene expression, an informative and accurate analysis, a specific analysis of the response to drugs.
Accelerate Research and Practice in Biomarker Research
Many kinds of RNAs have been used as biomarkers, among which mRNA is the most widely studied. In recent years, many important functional RNAs that do not encode protein have been discovered, some of which have also been used as biomarkers, including some microRNAs (miRNAs), piwi-separated RNAs (piRNAs), small nucleolar RNAs (snoRNAs), long noncoding RNAs (IncRNAs) and circular RNAs (circRNAs). ncRNAs are very stable molecules, which represents a very important prerequisite for an excellent biomarker. In addition, RNA sequencing analysis can be used for studying regular variation events, such as alternative splicing and gene fusion, both of which may be associated with disease prognosis.
Based on our next-generation sequencing and long-read sequencing platforms, CD Genomics provides a complete solution for biomarker research. Our one-stop service can help you purify high-quality nucleic acids from a variety of research sample types, and use illumina next-generation sequencing, 10x Genomics single-cell sequencing, PacBio sequencing, and Nanopore direct RNA sequencing to provide accurate sequencing results. After bioinformatics analysis, Finally, provide customized reports and serve your scientific research work.
Our advantages
An abundance of sample handling experience
Enrichment and extraction of low-abundance RNAs
Multiple sequencing platforms to choose from
High accuracy of sequencing results
Comprehensive bioinformatics analysis and customized analysis
The issues that can be addressed with our RNA sequencing services
Genetic and epigenetic mechanisms of gene regulation
Disease diagnosis and prognosis
Drug resistance research
Toxicity profiling with transcript analysis
Decoding genomic information for drug discovery
Note: Our services are for research use only, not for disease diagnosis and treatment.
What can we do?
Sequencing targets: mRNA,tRNA,miRNAs, piRNA, snoRNA, IncRNA, circRNA Sample types: various sample types such as urine, saliva, serum or blood, and tissues Data delivery: identification, quantitation, differential expression analysis, and other bioinformatics analyses
Filtering, trimming, optional error correction if possible, and visualization
Transcriptome Assembly
Mapping to known transcriptomes; de novo assembly and annotation; outcome evaluation; Transcript and isoform quantification
Functional Profiling
GO, DAVID, KEGG, TrEMBL, Pfam, InterPro, SignalP, Blast2GO; Molecular functions or pathways in which differentially expressed genes
Other advanced Analysis
In-depth and advanced analyses: Gene fusion analysis, single nucleotide variant analysis, differential transcript expression, ncRNA-gene interaction network
Comprehensive Solutions to Accelerate Your Biomarker Research
CD Genomics has a professional technical team and bio-analysis team, and has more than ten years of project experience in the sequencing field. We have a mature technical route, provide accurate and reliable data and deliver results that meet your requirements. We are committed to providing efficient, cost-effective, and high-quality sequencing services to help your research of biomarkers.
* For Research Use Only. Not for use in diagnostic procedures.
